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Red Cell Components

 

Documentation and Monitoring

  • Monitor patient during and after transfusion for signs of a reaction
  • Document vital signs before, during, and after transfusion
  • Record volume administered and transfusion reaction per nursing protocol

Type of Components

  Volume/Unit
Whole Blood
450-550 mL
Red Blood Cells
200-250 mL
Red Blood Cells in additive solution
300-400 mL
Leukocyte-Reduced Red Blood Cells in additive solutions
240-280 mL
Frozen Deglycerolized Red Blood Cells
180-250 mL
Washed Red Blood Cells
180-250 mL

Compatibiltiy

WHOLE BLOOD

  • ABO-Whole Blood MUST be group-specific

RED CELL COMPONENTS

  • ABO - For red cell components, compatibility is as follows:
Patient Group
Compatible Donor Groups for Plasma*
A
A, O
B
B, O
AB
A, B, AB, O
O
O

Rh

  • All transfusions should be Rh compatible
  • Rh-negative red cells can be given to Rh-positive patients
  • NOTE: In certain circumstances, such as bleeding emergencies, Rh-positive red cells can be given to Rh-negative patients

Compatibiltiy Testing

  • Crossmatching must be performed for all whole blood and red cell components
  • Type and Screen should be ordered if transfusion is possible but unlikely
  • Type and Cross should be ordered if transfusion is likely

Storage Temperature

  • Red cell components MUST be stored in a blood bank monitored (1-6C) refrigerator
  • If the component cannot be infused immediately return it to the blood bank within 30 minutes for appropriate storage

Notes

  • FILTERS
    ALL red cell components must be administered through a standard (170micron) or leukocyte reduction filter

    Leukocyte reduction filters designed to be used for platelets must NOT be used for red cells
  • TIME OF INFUSION
    Components Should be infused within 4 hours
  • MEDICATION
    DO NOT add medication to whole blood or red cell components
  • PUMPS
    Acceptable for use with platelets
  • COMPATIBLE INTRAVENOUS SOLUTIONS
    .09% NaCl injection, USP may be added to Red Blood Cells if indicated to reduce viscosity

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